![]() Infants infected with influenza A were monitored for symptoms including fever, cough and wheezing. The infants were randomized into low-dose and high-dose vitamin D groups, and serum calcium, inorganic phosphorus and 25-hydroxyvitamin D levels were detected thrice in 4 months. This study aimed to evaluate the clinical efficacy and safety of vitamin D for preventing influenza A in 400 infants in a multicenter, randomized, open, controlled clinical trial. The work cannot be changed in any way or used commercially without permission from the journal. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. ![]() wrote the manuscript.Īddress for correspondence: Hailong Lin, MD, Department of Pediatrics, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, 109th Xueyuanxi Road, Wenzhou, Zhejiang Province, China. ![]() contributed reagents/materials/analysis tools and J.Z. performed the experiments J.D., L.H., Y.W. conceived and designed the experiments J.Z., J.D., L.H., Y.W., Y.S. The authors have no conflicts of interest to disclose. All procedures involving human participants were performed in accordance with the 1964 Helsinki declaration and its later amendments, or comparable ethical standards. The present study was approved by The First People’s Hospital of Yongkang Institutional Ethics Committee (approval number: 1-2015-11). ‡Department of Pediatrics, Jinhua People’s Hospital, Jinhua, China.Īccepted for publication September 25, 2017. †Department of Pediatrics, The Second Affiliated Hospital and Yuying Children’s Hospital of Wenzhou Medical University, Wenzhou, China From the *Department of Pediatrics, The First People’s Hospital of Yongkang, Yongkang, China
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